In challenging times like what we now have, both the medical and the scientific community, the private and the government sectors have combined their forces and efforts for one ultimate goal – and that is to find the one vaccine that will put an end to the COVID-19 pandemic.
In light of this comprehensive study and research, plenty of drugs are now being tested by these bodies to see if any of them can be taken advantage of in the fight against the Coronavirus. However, there is a different light at the end of the tunnel. Researchers are looking into the possibility of blocking testosterone as a way of preventing men from getting infected.
Researchers found out that men from Italy diagnosed with prostate cancer and are taking androgen-deprivation therapy or ADT have lesser chances of getting infected with COVID-19. And if ever they get the virus, they seem to have less severe cases.
An oncologist from the Università della Svizzera Italiana in Bellinzona, Switzerland Dr. Andrea Alimonti, firmly believes how testosterone replacement therapy Sydney could be worth trying on men who are suffering from the severe symptoms of COVID-19.
This brings us to think that TRT Australia procedure can be taken advantage of as a therapeutic window for treating patients that have been infected with the virus but haven’t gotten better. But these medical professionals need to see first if TRT will help their patients recover faster or if it will just alleviate their symptoms.
After Alimonti saw the data showing that men are more likely to get infected with the COVID-19 virus as opposed to women and that they tend to suffer more from the bouts with the disease, his interest was piqued.
His study led him to conclude that the COVID-19 needs a particular enzyme (TMPRSS2) to infect cells and that it can get blocked by the ADT (androgen-deprivation therapy). For many years and counting, the medical sphere has known all along that ADT can get in the way of the level of this enzyme.
The speculation that Alimonti has about it is that androgen levels are taking control over this enzyme, explaining the reason why men are more prone to be infected by the virus and eventually develop more serious symptoms, compared to women.
With regard to this retrospective study, Alimonte is not fully convinced that TRT can be used to treat or possibly prevent COVID-19. At the moment, there is no way we can prove that it will be beneficial to non-prostate cancer patients. But we know that it will require further validation and only a prospective clinical study about it will help in bringing us there.
Further investigation into this showed that cancer patient men are two times more susceptible to catch a COVID-19 infection, but only 4 men taking ADT became infected. None of them died, though.
When his research looked at around 37,000 prostate cancer patients but were not into ADT, 114 of them got infected by the virus and 18 perished. But with 79,000 cancer patient men (other than prostate cancer), 312 of them acquired the COVID-19, and 57 of them died.
A professor from the Harvard Medical School in Boston, Dr. Anthony D’Amico believes that there could be some other ways to explain why prostate cancer patients have lesser chances of acquiring COVID-19.
One is that men suffering from prostate cancer and are given ADT are not immunosuppressed as to how some patients of other forms of cancer are. Second is that they can take a shot of ADT and after which they can remain home.
This is unlike patients with another type of cancer which may necessitate them to make frequent hospital trips for medication or chemotherapy, in which case they are likely to place them at a higher risk for infection.
Since the study is still in its preliminary stage, we can’t have it yet as a definitive reason to change treatment plans for COVID-19 patients or take ADT as an alternative treatment plan for them. ADT in itself comes with its own array of side effects, and it is too premature, too soon to begin to see it that way.
With regard to how relevant testosterone replacement therapy Sydney is in our fight against this pandemic, it is hard to tell yet since the available data we have at the moment will not suffice to come up with a strong conclusion.